ACMJ
Anatolian Current Medical Journal

Anatolian Current Medical Journal (ACMJ) is an unbiased, peer-reviewed, and open access international medical journal. The Journal publishes interesting clinical and experimental research conducted in all fields of medicine, interesting case reports, and clinical images, invited reviews, editorials, letters, comments, and related knowledge.

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Original Article
Risk factors for post-transplant diabetes mellitus in kidney transplant recipients: a single-center retrospective study
Abstract
Aims: Kidney transplantation is one of the preferred treatment modalities in end-stage renal disease (ESRD) and significantly preserves kidney function and the patient's quality of life. However, post-transplant diabetes mellitus (PTDM) is a common complication, occurring in approximately one-third of renal transplant recipients. The main aims of our study were to determine the risk factors associated with the development of PTDM in renal transplant patients, to demonstrate its incidence, and to evaluate its long-term consequences on graft and patient survival. Methods: This single-center retrospective study included 242 non-diabetic kidney transplant recipients who underwent transplantation between January 2014 and December 2022. Patients with pre-existing diabetes, younger than 18 years old, multiple transplants or graft survival of less than one year were excluded. Demographic data, immunosuppressive regimens, perioperative glucose levels and laboratory findings were collected. All patients classified as having PTDM required glucose lowering treatment—either oral antidiabetic agents or insulin—initiated after the third month post-transplant, confirming the persistence of hyperglycemia beyond the early postoperative period. Statistical analysis were performed using IBM SPSS 22 with categorical variables compared using Pearson Chi-square test and continuous variables using Mann-Whitney U test. ROC analysis logistic regression were conducted to identify risk factors for PTDM. Results: PTDM developed more frequently in older (45 vs. 33 years, p

Keywords : Kidney transplantation, post-transplant diabetes mellitus, risk factors, body mass index, coronary artery disease

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Article available in :
Volume 7, Issue 6, 2025
Page : 933-939
https://doi.org/10.38053/acmj.1796033
Article Information
Received : 03 Eki 2025
Accepted : 26 Eki 2025
Published : 26 Eki 2025
Corresponding Author :

Ümit Çakmak: Department of Nephrology, Memorial Antalya Hospital, Antalya, Turkiye

[email protected]
Citation : Çakmak Ü, Merhametsiz Ö, Akkaya S, Ay N. Risk factors for post-transplant diabetes mellitus in kidney transplant recipients: a single-center retrospective study. Anatolian Curr Med J. 2025;7(6):933-939. doi:10.38053/acmj.1796033

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