ACMJ
Anatolian Current Medical Journal

Anatolian Current Medical Journal (ACMJ) is an unbiased, peer-reviewed, and open access international medical journal. The Journal publishes interesting clinical and experimental research conducted in all fields of medicine, interesting case reports, and clinical images, invited reviews, editorials, letters, comments, and related knowledge.

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Original Article
High versus low dialysate sodium: a single-center small-scale prospective study
Abstract
Aims: The matter of dialysate sodium concentration has become progressively substantial in the last 50 years, when dialysis modalities have advanced quickly. In many studies, it has been established that dialysate sodium value is correlated with blood pressure alternance, hypervolemia, interdialytic weight gain (IDWG), and chronic inflammation. However, there is no clear knowledge about its direct effect on inflammation. In this study, we profited from high-sensitivity C-reactive protein (hs-CRP), which is a helpful marker, to survey the inflammation correlation with dialysate sodium (DNa).
Methods: 109 non-diabetic hemodialysis patients were enrolled in the study. All patients participating in the study were new onset, less than 6 months dialysis patients and met Kt/V of 1.4 at minimum criteria.
Results: They were divided into two groups: group 1, low dialysate sodium (137 mmol/L) and group 2, conventional dialysate sodium (140 mmol/L) and followed-up for two months. During the follow-up period, serum hs-CRP levels were measured and categorized as baseline, 1st month and second month level.
Conclusion: As a result, no statistically remarkable disparity between the groups were determined in terms of serum hs-CRP levels at baseline, 1st month, and 2nd month of the study (p>0.05). We did not establish any significant differences that would make it worth ignoring some symptoms symptoms such as cramps and hypotension.

Keywords : Chronic kidney disease, hemodialysis, dialysate sodium, chronic inflammation, high-sensitivity CRP

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Article available in :
Volume 7, Issue 2, 2025
Page : 196-200
https://doi.org/10.38053/acmj.1626469
Article Information
Received : 24 Oca 2025
Accepted : 05 Mar 2025
Published : 21 Mar 2025
Corresponding Author :

Sara İleri: Department of Nephrology, Gülhane Training and Research Hospital, University of Health Sciences, Ankara, Turkiye

[email protected]
Citation : İleri S. High versus low dialysate sodium: a single-center small-scale prospective study. Anatolian Curr Med J. 2025;7(2):196-200.

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