ACMJ
Anatolian Current Medical Journal

Anatolian Current Medical Journal (ACMJ) is an unbiased, peer-reviewed, and open access international medical journal. The Journal publishes interesting clinical and experimental research conducted in all fields of medicine, interesting case reports, and clinical images, invited reviews, editorials, letters, comments, and related knowledge.

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Original Article
Evaluation of prenatal-postnatal outcomes and risk factors in fetal jejunoileal atresia
Abstract
Aims: The aim of the current study is to reveal ultrasonographic and clinical features, evaluation of prenatal-postnatal outcomes and risk factors of fetal jejunoileal atresia.
Methods: This retrospective study evaluated all cases of fetal jejunoileal atresia identified between 2018 and 2024 at a tertiary centre of maternal-fetal medicine. In all cases, the pediatric surgery team confirmed the definitive diagnosis of jejunoileal atresia during the postnatal period. The cohort was divided into two groups, the "poor outcome" and "good outcome", in order to compare and evaluate risk factors determining the outcome.
Results: During the study period, a total of 18 cases were recorded. All cases in the cohort managed to reach live birth. 15 (83.3%) neonates survived after the surgical procedure, whereas 3 (16.7%) neonates were deceased during the post-operative period. Short bowel syndrome was diagnosed in 2 (11.1%) living cases during postoperative follow-ups. <80 cm intact bowel length predicts poor outcome with 80% sensitivity and 92.3% specificity (p<0,015). The distance of the most proximal point of atresia to Treitz <40 cm predicts poor outcome with 80% sensitivity and 69.2% specificity (p<0,025).
Conclusion: Fetal jejunoileal atresia still has high mortality and morbidity rates despite improved technology, surgical techniques and advanced postoperative care. Therefore, it is very important that the delivery and particularly surgical procedure should be performed by an experienced surgical team in well-equipped centers.

Keywords : Fetal jejunoileal atresia, prenatal diagnosis, outcome, risk factors

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1. Galani A, Zikopoulos A, Papandreou L, Mastora E, Zikopoulos K, Makrydimas G. Prenatal diagnosis of fetal jejunal atresia: a case report. Cureus. 2021;13(10):e18947.
2. Burjonrappa SC, Crete E, Bouchard S. Prognostic factors in jejuno-ileal atresia. Pediatr Surg Int. 2009;25(9):795-798. doi:10.1007/s00383-009-2422-y
3. Schmedding A, Hutter M, Gfroerer S, Rolle U. Jejunoileal atresia: a national cohort study. Front Pediatr. 2021;9:665022.
4. Burjonrappa S, Crete E, Bouchard S. Comparative outcomes in intestinal atresia: a clinical outcome and pathophysiology analysis. Pediatr Surg Int. 2011;27(4):437-442. doi:10.1007/s00383-010-2729-8
5. Xiong X, Lu W, Xing F, et al. Clinical characteristics of postoperative necrotizing enterocolitis in patients with congenital jejunoileal atresia and its risk factors. World J Pediatr Surg. 2024;7(1):e000622.
6. Virgone C, D&#39;antonio F, Khalil A, Manzoli L, Giuliani S. Accuracy of prenatal ultrasound in detecting jejunal and ileal atresia: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2015;45(5):523-529.
7. Iacobelli BD, Zaccara A, Spirydakis I, et al. Prenatal counselling of small bowel atresia: watch the fluid! Prenat Diagn. 2006;26(3):214-217.
8. Dalla Vecchia LK, Grosfeld JL, West KW, Rescorla FJ, Scherer L, Engum SA. Intestinal atresia and stenosis: a 25-year experience with 277 cases. Arch Surg. 1998;133(5):490-497.
9. Stollman TH, de Blaauw I, Wijnen MH, et al. Decreased mortality but increased morbidity in neonates with jejunoileal atresia; a study of 114 cases over a 34-year period. J Pediatr Surg. 2009;44(1):217-221.
10. R&oslash;kkum H, Johannessen H, Bj&oslash;rnland K. Perioperative and long-term outcome in patients treated for jejunoileal atresia. J Pediatr Gastroenterol Nutr. 2023;76(4):434-439.
11. Tahkola E, Luoto T, Pakarinen MP. Management and outcomes of intestinal atresia-a single institution experience from 1947 to 2019. J Pediatr Surg. 2024;59(11):161622.
12. Kurdi M, Mokhtar A, Elkholy M, et al. Antimesenteric sleeve tapering enteroplasty with end-to-end anastomosis versus primary end-to-side anastomosis for the management of jejunal/ileal atresia. Asian J Surg. 2023;46(9):3642-3647.
13. Aboalazayem A, Ragab M, Magdy A, Bahaaeldin K, Shalaby A. Outcome of tapering enteroplasty in managing jejunoileal atresia. J Indian Assoc Pediatr Surg. 2022;27(6):666-669.
14. Takahashi D, Hiroma T, Takamizawa S, Nakamura T. Population-based study of esophageal and small intestinal atresia/stenosis. Pediatr Int. 2014;56(6):838-844.
15. Casaccia G, Trucchi A, Nahom A, et al. The impact of cystic fibrosis on neonatal intestinal obstruction: the need for prenatal/neonatal screening. Pediatr Surg Int. 2003;19(1-2):75-78.
16. Casaccia G, Trucchi A, Spirydakis I, et al. Congenital intestinal anomalies, neonatal short bowel syndrome, and prenatal/neonatal counseling. J Pediatr Surg. 2006;41(4):804-807.
Article available in :
Volume 7, Issue 1, 2025
Page : 84-88
https://doi.org/10.38053/acmj.1602139
Article Information
Received : 15 Ara 2024
Accepted : 09 Oca 2025
Published : 10 Oca 2025
Corresponding Author :

Ümit Taşdemir: Department of Perinatology, Zeynep Kamil Women and Children's Diseases Training and Research Hospital, İstanbul, Turkiye

[email protected]
Citation : Taşdemir Ü, Eyisoy ÖG, Gezer M, Celayir A, Eriç Özdemir M, Demirci O. Evaluation of prenatal-postnatal outcomes and risk factors in fetal jejunoileal atresia. Anatolian Curr Med J. 2025;7(1):84-88.

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