ACMJ
Anatolian Current Medical Journal

Anatolian Current Medical Journal (ACMJ) is an unbiased, peer-reviewed, and open access international medical journal. The Journal publishes interesting clinical and experimental research conducted in all fields of medicine, interesting case reports, and clinical images, invited reviews, editorials, letters, comments, and related knowledge.

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Original Article
Assessment of tumor location in adjuvant treatment decision for stage II colon cancer
Abstract
Aims: In stage II colon cancer, the aim is to evaluate the impact of tumor location and other clinicopathological factors on prognosis and survival.
Methods: The study included a total of 93 patients diagnosed with stage II colon cancer between January 2018 and December 2022, comprising 41 females and 52 males. Clinicopathological factors related to the patients were retrospectively investigated. Factors found to be significant in univariate analysis were further evaluated through multivariate analysis to identify independent factors.
Results: As a result of univariate analysis, variables such as tumor location (right-left colon), perineural invasion, surgical margin, intestinal obstruction, and lymph node dissection were found to be statistically significant for the risk of death (p<0.05). These variables, identified as significant in univariate analyses, were included in the multivariate cox regression model. According to the result of the multivariate cox regression model, individuals with intestinal obstruction were determined to have a 7.07 times higher risk of death (HR: 7.07; 95% CI: 2.42-20.62; p<0.001).
Conclusion: We observed an association between left colon tumors in stage II patients and poorer survival, and we noted that intestinal obstruction has an independent prognostic effect on survival.

Keywords : Adjuvant chemotherapy, colon cancer, prognosis, tumor localization

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Article available in :
Volume 6, Issue 5, 2024
Page : 293-298
https://doi.org/10.38053/acmj.1482701
Article Information
Received : 13 May 2024
Accepted : 03 Ağu 2024
Published : 30 Eyl 2024
Corresponding Author :

Şafak Yıldırım Dişli: Department of Medical Oncology, Kayseri City Hospital, Kayseri, Turkiye

[email protected]
Citation : Yıldırım Dişli Ş, Ayas E, Dişli AK, Doğan E, Özdemir F. Assessment of tumor location in adjuvant treatment decision for stage II colon cancer. Anatolian Curr Med J. 2024;6(5):293-298.

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