ACMJ
Anatolian Current Medical Journal

Anatolian Current Medical Journal (ACMJ) is an unbiased, peer-reviewed, and open access international medical journal. The Journal publishes interesting clinical and experimental research conducted in all fields of medicine, interesting case reports, and clinical images, invited reviews, editorials, letters, comments, and related knowledge.

eISSN: 2718-0115
Creative Commons CC BY-NC-ND 4.0 International License.
EndNote Style

Submit Manuscript

Index
Araştırma Makalesi
Postmenopausal lipid profile changes
Abstract
Aim: It has been reported that total cholesterol, triglyceride and low density lipoprotein cholesterol (LDL-C) increase with menopause, while high-density lipoprotein (HDL-C) gradually decreases. In this study, we aimed to investigate lipid levels in postmenopausal patients. Material and Method: Forty-three postmenopausal women and 43 healthy women were included in the control group and a similar body-mass index and age group. Blood samples were taken after fasting for 12 hours. Triglyceride, total cholesterol, and HDL-C plasma concentrations were measured by cholesterol enzymatic tests, calculated by the LDL-C Friedewald formula. Results: Triglyceride, total cholesterol and LDL-C levels were found to be increased during the postmenopausal period. HDL-C was found to be decreased in postmenopausal period. However, total cholesterol, LDL-C and HDL-C were not statistically significant. Triglyceride was statistically significantly higher in postmenopause group compared to control. When multiple regressions were made, triglyceride elevation in age, BMİ, gamma glutamyl transferase were independently detected in postmenopausal women. Conclusion: Menopause and triglyceride level sincreased significantly. Total cholesterol and LDL-C levels did not significantly decrease in HDL-C levels.

Keywords : Postmenopausal period, lipid levels, triglyceride

Download Article


1. Menopoz ve Kültür, Öteki Yayınevi, Tolga Ersoy 1998.
2. Marsh MS, Whitehead MI. Management of the menopause. British Medical Bull 1992; 48: 426–57.
3. Ahsen Şirin, Menopoz ve getirdiği sorunlar. Ege Üniversitesi Hemşirelik Yüksek Okulu Derg 1995; 11: 2.
4. Hotun N. Bir kilometre taşı. Menopoz. Çevik Matbaacılık. İstanbul, 1998.
5. Wang N, Qin MZ, Cui J. Lipid profile comparison between pre- and post-menopausal women, Zhonghua Xin Xue Guan Bing Za Zhi 2016 Sep 24; 44: 799-804.
6. Taleb-Belkadi O, Chaib H, Zemour L, Fatah A, Chafi B, Mekki K. Lipid profile, inflammation, andoxidative status in peri-and postmenopausal women, Gynecol Endocrinol 2016 Dec; 32: 982-5.
7. Zhang J, Wang H, Yang S, Wang X. Comparison of lipid profiles and inflammation in pre- and post-menopausal women with cerebral infarction and the role of atorvastatin in such populations, Lipids Health Dis 2018 Feb 2; 17: 20.
8. Teixeira N, Mourits MJ, Oosterwijk JC, et al. Cholesterol profile in women with prematüre menopause after risk reducing salpingo-oophorectomy. Fam Cancer 2018 Jun; 18: 19-27.
9. Shah MG, Maibach HI. Estrogen and skin, an overview, Am J Clin Dermatol 2001; 2: 143-50.
10. Palacios S, Henderson VW, Siseles N, Tan D, Villaseca P. Age of menopause and impact of climacteric symptoms by geographical region, Climacteric 2010; 13: 419–28.
11. Çiçek M, Akyürek C, Çelik Ç, Haberal A. Kadın Hastalıkları ve Doğum Bilgisi, Güneş Kitabevi Ankara, 2004.
12. Cooney MT, Dudina A, Whincup P, et al. Reevaluating the roseapproach: comparative benefits of the population and high risk prevent ivestrategies. Eur J Cardiovasc Prev Rehabil 2009; 16: 541–9.
Article available in :
Volume 1, Issue 1, 2019
Page : 1-4
https://doi.org/10.38053/agtd.482412
Article Information
Received : 13 Kas 2018
Accepted : 27 Ara 2018
Published : 22 Oca 2019
Corresponding Author :

Ahmet Veli Şanibaş: Sağlık Bilimleri Üniversitesi, Erzurum Bölge Eğitim ve Araştırma Hastanesi, İç Hastalıkları Kliniği, Erzurum, Türkiye

[email protected]
Citation : Kartal Baykan E, Karaüzüm Yalçın N, Şanibaş AV, Ertaş F, Çarlıoğlu A. Postmenopozal lipit profil değişiklilleri. Anadolu Güncel Tıp Derg 2019; 1(1): 1-4.

Read: 1852
Cited: 0
Download : 375
_Footer